The information on this website is centred around the topic of pragmatic trials. It can serve several purposes, be it to aid in the design of more pragmatic trials, to evaluate existing pragmatic trials or to be used as an educational resource for pragmatic trials.
Pragmatic trials aim to capture the true effect of a treatment strategy in the real world. As such, they provide a great opportunity to generate real-world evidence in the early stages of drug development.
However, pragmatic trials are still in their early days and experience with designing and executing these trials is limited. Therefore, the PragMagic Tool, a decision support tool and educational tool for pragmatic trial design and protocol evaluation, has been developed. Also, additional resources on specific challenges for pragmatic trials have been bundled on this website.